Plant Transcription Factor Database
Previous version: v3.0
Triticum urartu
FAR1 Family
Species TF ID Description
TRIUR3_00919-P1FAR1 family protein
TRIUR3_01111-P1FAR1 family protein
TRIUR3_03147-P1FAR1 family protein
TRIUR3_03202-P1FAR1 family protein
TRIUR3_03699-P1FAR1 family protein
TRIUR3_03719-P1FAR1 family protein
TRIUR3_03864-P1FAR1 family protein
TRIUR3_05031-P1FAR1 family protein
TRIUR3_05738-P1FAR1 family protein
TRIUR3_09592-P1FAR1 family protein
TRIUR3_10746-P1FAR1 family protein
TRIUR3_11036-P1FAR1 family protein
TRIUR3_11057-P1FAR1 family protein
TRIUR3_12316-P1FAR1 family protein
TRIUR3_13794-P1FAR1 family protein
TRIUR3_17083-P1FAR1 family protein
TRIUR3_17109-P1FAR1 family protein
TRIUR3_17271-P1FAR1 family protein
TRIUR3_17567-P1FAR1 family protein
TRIUR3_18592-P1FAR1 family protein
TRIUR3_18678-P1FAR1 family protein
TRIUR3_19482-P1FAR1 family protein
TRIUR3_19783-P1FAR1 family protein
TRIUR3_20488-P1FAR1 family protein
TRIUR3_20720-P1FAR1 family protein
TRIUR3_21266-P1FAR1 family protein
TRIUR3_21721-P1FAR1 family protein
TRIUR3_23095-P1FAR1 family protein
TRIUR3_23242-P1FAR1 family protein
TRIUR3_23344-P1FAR1 family protein
TRIUR3_25143-P1FAR1 family protein
TRIUR3_25572-P1FAR1 family protein
TRIUR3_27758-P1FAR1 family protein
TRIUR3_28019-P1FAR1 family protein
TRIUR3_32469-P1FAR1 family protein
TRIUR3_33125-P1FAR1 family protein
TRIUR3_33462-P1FAR1 family protein
TRIUR3_33674-P1FAR1 family protein
TRIUR3_33706-P1FAR1 family protein
TRIUR3_34907-P1FAR1 family protein
TRIUR3_34993-P1FAR1 family protein
TRIUR3_35437-P1FAR1 family protein
FAR1 Family Introduction

We show that Arabidopsis FHY3 and FAR1, which encode two proteins related to Mutator-like transposases, act together to modulate phyA signaling by directly activating the transcription of FHY1 and FHL, whose products are essential for light-induced phyA nuclear accumulation and subsequent light responses. FHY3 and FAR1 have separable DNA binding and transcriptional activation domains that are highly conserved in Mutator-like transposases. Further, expression of FHY3 and FAR1 is negatively regulated by phyA signaling. We propose that FHY3 and FAR1 represent transcription factors that have been co-opted from an ancient Mutator-like transposase(s) to modulate phyA-signaling homeostasis in higher plants.

We next used a yeast one-hybrid assay to delineate the DNA sequences to which FHY3 and FAR1 bind. GAD-FHY3 or GAD-FAR1 fusion proteins (GAD, GAL4 transcriptional activation domain), but not GAD alone, activated the LacZ reporter genes driven by the FHY1 and FHL promoters. Deletion analysis narrowed down the FHY3/FAR1 binding site to a 39-bp promoter subfragment located on the "a" fragment for both FHY1 and FHL. Notably, these subfragments share a stretch of consensus sequence, 5'-TTCACGCGCC-3'. Mutating the core sequence "CACGCGC" of this motif (m2 and m3 for FHY1, m5 for FHL) abolished the reporter gene activation by both GAD-FHY3 and GAD-FAR1. Mutating the flanking sequences (m1 and m4) did not obviously affect the reporter gene activation by GAD-FAR1, but clearly reduced activation by GAD-FHY3. Thus, "CACGCGC" likely defines a cis-element that confers specific binding for FHY3 and FAR1 and is named FBS for FHY3-FAR1 binding site.

Lin R, Ding L, Casola C, Ripoll DR, Feschotte C, Wang H.
Transposase-derived transcription factors regulate light signaling in Arabidopsis.
Science, 2007. 318(5854): p. 1302-5.
PMID: 18033885